Hugo Kubinyi Transporters as Drug Carriers

This reference handbook is the first to provide a comprehensive overview, systematically characterizing all known transporters involved in drug elimination and resistance. Combining recent knowledge on all known classes of drug carriers, from microbes to man, it begins with a look at human and mammalian transporters. This is followed by microbial, fungal and parasitic transporters with special attention given to transport across those physiological barriers relevant for drug uptake, distribution and excretion. As a result, this key resource lays the foundations for understanding and investigating the molecular mechanisms for multidrug resistance in cancer cells, microbial resistance to antibiotics and pharmacokinetics in general. For anyone working with antibiotics and cancer chemotherapeutics, as well as being of prime interest to biochemists and biophysicists.

23146.73 RUR

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Karobi Moitra ABC Transporters in Human Disease

Группа авторов Pumps, Channels and Transporters

Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions

12217.81 RUR

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Jamie Goode A. Epithelial Anion Transport in Health and Disease

Cl- absorption and HCO3- secretion are intimately associated processes vital to epithelial function, itself a key physiological activity. Until recently the transporters responsible remained obscure, but a breakthrough occurred with the discovery of the SLC26 transporters family. It is now clear that the SLC26 transporters have broad physiological functions since mutations in several members are linked to a variety of diseases. This book describes the properties of this family in detail, with contributions from the leading global researchers in the field. Complementary views from experts on other ion channels are offered in the discussions, which make fascinating reading. This family consists of at least 10 genes, each of which has several splice variants. Most members of the family are expressed in the luminal membrane of epithelial cells. Characterization of anion transport by three members has revealed that all function as Cl-/HCO3- exchangers, suggesting that SLC26 transporters are responsible for the luminal Cl-/HCO3- exchange activity. The SLC26 transporters are activated by the CF transmembrane conductance regulator and activate it in turn, leading to a model in which these molecules act together to mediate epithelial Cl- absorption and HCO3- secretion. The book includes chapters on the transport of other molecules by the SLC26 family, including oxalate in the kidney and sugars in cochlear hair cells amongst others. It also describes recent discoveries that most SLC26 transporters bind to scaffold proteins and that they all contain a conserved domain predicted to participate in protein-protein interactions. These suggest the SLC26 transporters exist in complexes with other Cl- and HCO3- transporters, and possibly other regulatory proteins. This book explores the functional role of these interactions, leading to better understanding of transepithelial fluid and electrolyte secretion and the diseases associated with it.

21093.39 RUR

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Группа авторов Transmembrane Transporters

A must-have far-reaching text that provides readers with a state-of-the-art molecule update on transmembrane transporters, focusing on the methodological approaches currently employed to better understand how transporters work and how they can be used in cutting edge therapies. Each chapter begins with an overview of the importnat biological questions presently being considered in their field, then presents scientific approaches to address these questions. In explaining approaches, the authors cover bench-top protocols, conceptual frameworks, data obtained, and pitfalls common to the techniques.

25106.74 RUR

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Ludman Harold S. ABC of Ear, Nose and Throat

This new edition of the best-selling ABC of Otolaryngology offers an up-to-date overview of otolaryngology, and head and neck surgery (ENT). Now in its fifth edition, the ABC of Ear, Nose and Throat advises on how best to manage patients with the most common ENT-related problems. Thoroughly revised and updated, this new edition includes extra chapters on facial pain, head and neck tumours, sleep apnoea and epistaxis, as well as recent advances in ENT evaluation and investigations (especially CT and MRI) and minimally invasive techniques. New material on voice, breathing and swallowing disorders, hearing impairment and cochlear implants has been added, with new pictures, illustrations and algorithms throughout. The ABC of Ear, Nose and Throat offers an essential introduction to this fundamental speciality for students, whilst providing a practical reference for GPs, GP registrars, junior doctors and nurses.

5875.35 RUR

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Robert Browning An Introduction to the Study of Robert Browning's Poetry

An Introduction to the Study of Robert Browning's Poetry by Robert Browning and Hiram Corson libreka classics – These are classics of literary history, reissued and made available to a wide audience. Immerse yourself in well-known and popular titles!

90.64 RUR

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Smithson W. Henry ABC of Epilepsy

ABC of Epilepsy provides a practical guide for general practitioners, and all those working in primary care, on the diagnosis, treatment and management of epilepsy, and for the continued monitoring and long term support of what is still a relatively poorly understood neurological disorder. This brand new title in the ABC series is highly illustrated throughout and presents what epilepsy is, its classification, and how to diagnose it. It covers anti-epileptic drugs and non-drug treatments, as well as self-management and living with epilepsy. Edited by a general practitioner and neurologist team, the ABC of Epilepsy reflects current NICE guidelines and is ideal for all GPs, primary health care professionals, practice nurses and specialist nurses, and non-specialist medical staff who play an increasing role in monitoring and managing of epilepsy patients.

3635.34 RUR

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Jones Eileen Progress with Oxford: abc. Age 3-4

Progress with Oxford: abc Age 3-4 builds alphabet skills while helping your child to work independently. Engaging activities, fun characters and stickers keep them motivated and a progress chart captures achievements. Additional activities and support on oxfordowl.co.uk help your child to make progress in knowing their abc whilst having fun.

583 RUR

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Bernard Valman ABC of One to Seven

The ABC of One to Seven is a practical guide to the management of common physical and emotional problems of early childhood. New chapters include the prevention and management of obesity, behavioural and emotional problems, ADHD, autism, the child with fever, and changes in access to medical and social services. Including the latest NICE guidelines and advice on when to refer and how to manage the problem afterwards, each chapter provides relevant websites and resources for health workers. The ABC of One to Seven and the companion book, ABC of the First Year, have become standard guides for general practitioners, trainee doctors, medical students, midwives, nurses and health visitors. They are indispensible reference books for family doctor surgeries, emergency and outpatient departments, wards and libraries.

5502.02 RUR

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ABC Transporters and Multidrug Resistance. Edited by ...

The Paris Declaration on Aid Effectiveness has been strongly criticized as both gender blind and for using a technocratic approach to measuring aid effectiveness.

Books by Jacques Robert (Author of L'évasion D'adolf Hitler)

Genres. Art; Biography; Business; Children's; Christian; Classics; Comics; Cookbooks; Ebooks; Fantasy

Robert Jacques | Facebook

Robert Jacques is on Facebook. Join Facebook to connect with Robert Jacques and others you may know. Facebook gives people the power to share and makes... Jump to. Sections of this page. Accessibility Help. Press alt + / to open this menu. Facebook. Email or Phone: Password: Forgot account? Robert Jacques. Robert Jacques is on Facebook. To connect with Robert, sign up for Facebook today. Log ...

Wiley: ABC Transporters and Multidrug Resistance - Ahcène ...

The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book ...

ABC Transporters and Multidrug Resistance - Ahcène ...

PART III ABC PROTEINS AND PATHOGENIC MICROORGANISMS. 6 ABC transporters and resistance to antibiotics (Serge Michalet and Marie-Geneviève Dijoux-Franca). 7 ABC proteins involved in protozoan parasite resistance (Bruno Pradines). PART IV MULTIDRUG RESISTANCE (MDR) MODULATION THROUGH INHIBITION OF ABC TRANSPORTERS: DESIGN OF INHIBITORS AND ...

Jacques Ibert – Wikipedia

Alexandra Laederich: Catalogue de l'œuvre de Jacques Ibert (1890–1962), in: Musikwissenschaftliche Publikationen, Bd. 9 (Hrsg.: Herbert Schneider), Georg Olms Verlag, Hildesheim/Zürich/New York, 1998, ISBN 3-487-10273-0; Weblinks. Werke von Jacques Ibert im Katalog der Deutschen Nationalbibliothek; Bühnenwerke

Jean-Robert Argand – Wikipedia

Jean-Robert Argand (* 18. Juli 1768 in Genf; † 13. August 1822 in Paris) war ein Buchhändler und Amateur mathematiker. Er ist der Sohn des Juweliers Jacques Argand (einem Verehrer von Jean-Jacques Rousseau) und Eve Carnac.

Wann ist ein Roboter ein Roboter? - Roboterwelt

Was macht eine Maschine zu einem Roboter? Wir sind der Frage nachgegangen und haben versucht, den Begriff des Roboters zu definieren.

Rodney Alcala - Wikipedia

Year(s) Event or victim name Offense; offender status/location 1961–64: U.S. Army 1968 Graduated from UCLA 1968 Tali Shapiro Rape, attempted murder; pleaded guilty to assault, 1971/California

Videos & Audios - Startseite | tagesschau.de

20.10.2020 22:35 Uhr. tagesthemen. Wie die Bewohner im Berchtesgadener Land mit den Ausgangsbeschränkungen umgehen, Kliniken in Belgien durch hohe Corona-Neuansteckungszahl unter Druck ...

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Jacques’ Wein-Depot | Weinhandlung in Rostock, Warnowufer 61

Jacques’ Wein-Depot in Rostock. Adresse: Warnowufer 61, 18057 Rostock. Die Weinhandlung in Ihrer Nähe.

Vincent Roberts - IMDb

Vincent Roberts, Actor: Take Down. Vincent Roberts was born on January 2, 1960 in Los Angeles, California, USA as Vincent M. Gogue. He was an actor, known for Take Down (1979), Lovely But Deadly (1981) and Centennial (1978). He died on November 22, 1981 in Los Angeles.

Jacques Robert – Filme, Biografien und Listen bei MUBI

Jacques Robert Drehbuchautor/in; Autor/in; Schauspieler/in; Alle anzeigen (25) Drehbuchautor/in. Vice Squad (Victims of Vice) Jacques Scandelari, 1978. Docteur Justice Christian-Jaque, 1975. Tödliche Begegnung Nicolas Gessner, 1971. Der grausame Job Édouard Molinaro, 1967. The Arnauds Léo Joannon, 1967. Ab heute wieder Niederschläge Marcel Ophüls, 1965. Der Zug zur Hölle Gilles Grangier ...

Jacques Robert » Bildershow

31 Mann - mit Sancho: Das ist der BVB-Kader für Bad Ragaz

List of Haitians - Wikipedia

This is a list of notable Haitian people. It includes people who were born in Haiti or possess Haitian citizenship, who are notable in Haiti and abroad. Due to Haitian nationality laws, dual citizenship is now permitted by the Constitution of Haiti, therefore people of Haitian ancestry born outside of the country are not included in this list, unless they have renounced their foreign ...

Robe Jacques Profile | Facebook

Profile von Personen mit dem Namen Robe Jacques anzeigen. Tritt Facebook bei, um dich mit Robe Jacques und anderen Personen, die du kennen könntest, zu...

Tourdaten, Konzertkarten & Live-Übertragungen von Vulcain

Finde Tourdaten und Konzerte von Vulcain in deiner Stadt. Schau dir mit Bandsintown Live-Übertragungen an, erhalte Updates zu den Künstlern, kaufe Karten und gib RSVPs zu Konzerten ab

ROBERT BENEDICT (agent) :: OpenCorporates

BENEDICT JACQUES ROBERT WALTER GODON, director, 13 Aug 2013 - , inactive branch VISION OVERSEAS HOTEL SERVICES LIMITED (United Kingdom, 7 Oct 2010-12 Jan 2016) BENEDICT JACQUES ROBERT WALTER GODON, director, 14 May 2009 - , inactive ABC PURCHASING LTD (United Kingdom, 14 May 2009-12 May 2015)

Andrea Zukowski – Manager – Jacques Robert | LinkedIn

Jacques Robert. Sept. 1986 – Heute 34 Jahre 2 Monate. Ausbildung. WU (Wirtschaftsuniversität Wien) WU (Wirtschaftsuniversität Wien) Magister rer. soc.oec Handelswissenschaften. 1976 – 1986. Sehen Sie sich Andrea Zukowskis vollständiges Profil an. nachzusehen, welche gemeinsamen Kontakte Sie haben; sich vorstellen zu lassen ; Andrea Zukowski direkt kontaktieren; Anmelden, um das ...

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<p>Tatar (upper body) won't play Thursday against Tampa Bay, Jean-Francois Chaumont of Le Journal de Montreal reports. Tomas Tatar is a famous Slovak professional ice hockey left winger player who currently plays for the Montreal Canadiens of the National Hockey League (NHL). He has two siblings named, Tibro Tatar and Marek Tatar. The information is also precise for Tomas Tatar’s. Check out ...

Der längste Tag: Amazon.de: John Wayne, Hans-Christian ...

Amazon.de: Finden Sie Der längste Tag in unserem vielfältigen DVD- & Blu-ray-Angebot. Gratis Versand durch Amazon ab einem Bestellwert von 29€.

Jean-Denis Robert

Alle Infos zu Jean-Denis Robert, bekannt aus Vincent, François, Paul und die anderen und Mado:

Schüler müssen auf Busse umsteigen - Lenninger Tal - Teckbote

Die Busse im Ersatzverkehr fahren jeweils an den Bahnhöfen in Kirchheim sowie in Oberlenningen zu den planmäßigen Abfahrtszeiten der Züge ab. Die Busse halten an den Haltestellen der Buslinie 177. In Kirchheim sind das der Busbahnhof, die Polizeiwache und die Straßenmeisterei. In Dettingen halten die Busse an den Haltestellen Robert-Bosch-Straße, Römerstraße, Volksbank, Obere Straße ...

Callot, Jacques: Illustration zu »Wunder des ...

Brockhaus-1911: Torre Annunziata · Callot · Callot-Hoffmann · Wunder · Sieben Wunder der Welt · Jacques · Jean Jacques. DamenConvLex-1834: Wunder der Welt · Rousseau, Jean Jacques · Delille, Jacques. Eisler-1912: Rousseau, Jean Jacques · Turgot, Anne Robert Jacques · Béguelin, Jacques · Novicow, Jacques. Heiligenlexikon-1858 ...

Callot, Jacques: Illustration zur Tragödie »Soliman« [1 ...

Brockhaus-1911: Soliman · Tragödie · Callot · Callot-Hoffmann · Jean Jacques · Jacques · Illustration. DamenConvLex-1834: Tragodie · Trauerspiel oder Tragödie · Delille, Jacques · Rousseau, Jean Jacques. Eisler-1912: Rousseau, Jean Jacques · Turgot, Anne Robert Jacques · Béguelin, Jacques · Novicow, Jacques. Heiligenlexikon-1858 ...

Jacques-Paul Bertrand - Moviepilot

Alle Infos zu Jacques-Paul Bertrand, bekannt aus Spion zwischen zwei Fronten und So Sweet and So Perverse:

Konzertveranstaltungen in Niederösterreich | Regionews.at

Morgen, Mittwoch, 21. Oktober, ist ab 20 Uhr im Stadttheater Wiener Neustadt mit „The King of Queen“ ein Freddy-Mercury-Tribute-Konzert angesetzt. Nähere Informationen und Karten unter 02622 ...

Ticketshop - Alle Events

Hommage à Jacques Brel - Robert Frank Jacobi singt Brel auf Alemannisch. Frank Jacobi. Riegel am Kaiserstuhl. Theater Kumedi. ab 21,00 € * Tickets. Riegel am Kaiserstuhl. Tickets. So. 08.11.2020 um 18:00 Uhr. Wo der Wein fehlt, da ist der Himmel der Menschheit wüst und leer ( Euripides) - Ein literarischer Kellerspaziergang. Ullo von Peinen. Riegel am Kaiserstuhl. Theater Kumedi. ab 21,00 ...

Robert Jacques in Medicine Hat AB T1B1V9 | Canada411.ca

Contact information for Robert Jacques in Medicine Hat, Alberta (AB), T1B1V9 | Canada411.ca

Le retour d'Ivanohë, pt. 1 (feat. Jean Claudric et son ...

Entdecken Sie Le retour d'Ivanohë, pt. 1 (feat. Jean Claudric et son orchestre) von Jacques Toja, Robert Manuel bei Amazon Music. Werbefrei streamen oder als CD und MP3 kaufen bei Amazon.de.

Jacques Neilz on TIDAL

Jacques Neilz. Play on TIDAL or open in our Desktop app Share. Top Tracks. Présentation générale & Annonce: E. Lalo, Le Roi d'Ys (Ouverture) Jacques Neilz. Lalo - Ravel - Debussy - Saint-Saëns - Roussel Credits View all ...

Ferienwohnungen in Tartane | Urlaub ab 45 EUR/Nacht ...

Wählen Sie aus 40 Apartments in Tartane aus. Unvoreingenommene Gästebewertungen und hochwertige Fotos helfen Ihnen, die beste Unterkunft zu finden. Zahlen Sie nicht zu viel! Wir bieten einfache und sichere Buchung ohne versteckte Gebühren.

Jacques Villeneuve zu Ferrari: Entscheidender Fehler ...

Der Kanadier Jacques Villeneuve legt den Finger dorthin, wo es wehtut: Der Formel-1-Weltmeister von 1997 sagt, wieso Ferrari in den vergangenen Jahren einen entscheidenden Fehler gemacht hat.

Hotels in Tartane, Martinique | Urlaub ab 39 EUR/Nacht ...

Planen Sie einen Urlaub in Martinique? Sichern Sie sich die besten Angebote unter 78 Hotels in Tartane. 20 Bewertungen helfen Ihnen, Ihre perfekte Unterkunft zu finden. Profitieren Sie von unserem einfachen und sicheren Buchungsprozess ohne zusätzliche Gebühren!

Inquest into Kirra-Lea McLoughlin's death told of 'some ...

A top neurosurgeon will give evidence at the inquest into the death of Kirra-Lea McLoughlin today after a detective yesterday told the hearing he believed there had been "some form of struggle" at ...

Gay Lussac - Ulm

Ab 1809 arbeitete er an der Gewinnung von reinem Kalium und reinem Bor und untersuchte die Eigenschaften von Chlor und Cyanwasserstoffsäure (HCN). Zusammen mit dem französischen Wissenschaftler Louis Jacques Thénard gelang es erstmals das Element Bor zu isolieren. Auf dem Gebiet der technischen Chemie entwickelte er zahlreiche Verbesserungen für die unterschiedlichsten Herstellungs- und ...

Robert Fripp's Diary - DGM Live

Toyah & Robert’s Sunday Lunch for September 13 th. featured a performance of Wild Thing, a hit for The Troggs in 1966 and played by Hendrix at Montery in 1967… The model for our performance is that of Reg and the boys. The original guitar part, and its tuning, is not convincingly rendered in NST. So, I tuned my second 1959 Les Paul, bought ...

Table Lamps – GUBI Webshop

Designed by Robert Dudley Best €769.00. BL1 Table Lamp - 16cm diameter

Release “Serge Reggiani” by Serge Reggiani - MusicBrainz

Format: CD, Year: 1987, Label: Disques Jacques Canetti (191 912), Barcode: 3229261919129, Length: 37:25


Scholarly & peer-review only Full text only Exclude Newspapers

Au Bout De Mes Rêves — Jean-Jacques Goldman | Last.fm

Schau das Video für Au Bout De Mes Rêves von Jean-Jacques Goldman's Intégrale 81-91 kostenlos und sieh dir Coverbilder, Songtexte und ähnliche Künstler an.

Château de Beaucastel 'Hommage à Jacques Perrin' 2010 ...

Jan 30, 2013 - Château de Beaucastel 'Hommage à Jacques Perrin' 2010 , Das Privileg einen der besten Weine der Welt zu trinken, der die legendären 100 Parker Punkte erreicht hat, das haben nur ganz wenige Wein-Genießer in dieser Welt.

Leben - db0nus869y26v.cloudfront.net

Robert IV. de La Marck (deutsch: Robert IV. von der Mark; * 15.Januar 1512 in Sedan; † 1556 in Guise) war Herr von Sedan und ab Juli 1552 Herzog von Bouillon.Ab 1547 bekleidete er das Amt des Marschalls von Frankreich.. Leben. Er war der Sohn Roberts III. de La Marck und der Guillemette von Saarbrücken.. Am 8. November 1538 heiratete er Françoise de Brézé, Gräfin von Maulévrier aus dem ...

Australian great Lisa Sthalekar inducted into ICC Cricket ...

Brilliant South African all-rounder Jacques Kallis and stylish Pakistan batsman Zaheer Abbas were also named as inductees by the ICC. AAP/ABC Posted 6 m minutes ago Sun Sunday 23 Aug August 2020 ...

Jacques Zoua » Bildershow

Jacques Zoua vom 1. FC Kaiserslautern schirmt den Ball gegen Aues Sebastian Hertner (r.) ab. (10.12.2016) imago/Picture Point LE . 10.12.2016. imago/Jan Huebner. 21.09.2016. Der Geschmähte trifft. Hamburgs Jacques Zoua musste in dieser Spielzeit viel Kritik über sich ergehen lassen. Gegen Borussia Mönchengladbach zeigte er endlich einmal seine Qualitäten und traf zum zwischenzeitlichen 0:1 ...

Dors Bébé, Dors — Jean-Jacques Goldman | Last.fm

Schau das Video für Dors Bébé, Dors von Jean-Jacques Goldman's Intégrale 81-91 kostenlos und sieh dir Coverbilder, Songtexte und ähnliche Künstler an.

TMDb.pro - Territory Movie Database - Downloadcenter

Alter: ab 12 Jahren . Regie: Robert Guédiguian . Darsteller: Ariane Ascaride, Jean-Pierre Darroussin, Gérard Meylan, Jacques Boudet, Anaïs Demoustier, Robinson Stévenin, Yann Trégouët, Geneviève Mnich, Fred Ulysse, Diouc Koma . Suisa-Nr.: 1012.160 . Leider ist zu diesem Film auf TMDb kein Material verfügbar. Synopsen, Fotos, Trailer, Filmkritiken, das Kinoprogramm oder Interviews zu ...

Jacques-Beauchamp - twitter-trends.de 2.0

Jacques-Beauchamp. Das Bild Jacques-Beauchamp von Marco Verch kann unter Creative Commons Lizenz genutzt werden. Es ist auf Flickr in voller Auflösung verfügbar. Lizenz-Beispiel und HTML-Code Photo: Jacques-Beauchamp by Marco Verch under Creative Commons 2.0

Robert Burns Poems and Songs of Robert Burns

Poems and Songs of Robert Burns libreka classics – These are classics of literary history, reissued and made available to a wide audience. Immerse yourself in well-known and popular titles!

90.64 RUR

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ABC. From the Hermitage Museum Collections

Teach your children the ABC and introduce them to some of the world's great masterpieces. Russia's first Museum ABC miniature book illustrates the alphabet with works from Russia's famous Hermitage Museum in Saint Petersburg.

230 RUR

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ABC featuring works of art from the State Hermitage. St. Petersburg

Teach your children the ABC and introduce them to some of the world's great masterpieces. Russia's first Museum ABC miniature book illustrates the alphabet with works from Russia's famous Hermitage Museum in Saint Petersburg.

690 RUR

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Colvin Lesley A. ABC of Pain

Chronic pain is a very common problem, impacting on many patients. Assessment and management can be challenging. The ABC of Pain focuses on the pain management issues often encountered in primary care. Covering major chronic pain presentations, such as musculoskeletal pain, low back pain and neuropathic pain, the ABC of Pain also provides guidance on the management of pain in pregnancy, children, older adults, drug dependency and the terminally ill. Beginning with an overview of the epidemiology of chronic pain, pain mechanisms and the assessment of pain, it then provides practical guidance on interventional procedures and methods of effective pain management. The ABC of Pain is a comprehensive, evidence-based reference. It is ideal for GPs, junior doctors, nurse specialists in primary care, palliative care specialists, and also hospital and hospice staff managing chronically and terminally ill patients.

4475.35 RUR

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ABC from The Hermitage Museum Collections

Teach your children the ABC and introduce them to some of the world's great masterpieces. Russia's first Museum ABC miniature book illustrates the alphabet with works from Russia's famous Hermitage Museum in Saint Petersburg.

288 RUR

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Robert Browning The Essential Robert Browning Collection


230.31 RUR

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Ho Jannie Vehicles ABC

Vehicles ABC is the fourth in this series of fun first alphabet books for babies and toddlers. As well as first letter sounds to say out loud, there are bright pictures featuring lots of familiar vehicles to spot and talk about, providing hours of first-word fun!

855 RUR

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Robert Browning The Love Letters of Robert Browning and Elizabeth Barrett Barrett

Robert E. Lee Recollections and Letters of General Robert E. Lee (Unabridged)

Animal ABC

Animal ABC is the third in this series of fun first alphabet books for babies and toddlers. As well as first letter sounds to say out loud, there are bright pictures featuring lots of familiar animals to spot and talk about, providing hours of first-word fun!

855 RUR

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